";s:4:"text";s:11135:"A Crack in Creation: Gene Editing and the Unthinkable Power to Control Evolution by Jennifer A. Doudna – eBook Details. p. 16. Nevertheless, a great read. The section on the history of gene editing felt more like a list of scientists than a recounting of additive knowledge; I would have preferred the latter. The book is very well written, and you get to read the human story of the excitement and interaction of the researchers along with gene editing presented in a way that someone like myself with a reasonable science background but not an expert can understand. A Crack in Creation combines two distinct, but related, books. In fact, genetics wasnt even on her radar. This book is divided into two equally important and engaging parts: a) the discovery and potential uses of CRISPr and b) the ethic considerations involved. To see what your friends thought of this book, With a basic knowledge and interest in biology and maybe the willingness to search on Google if in doubt, I think this book should be accessible to ev. A trailblazing biologist grapples with her role in the biggest scientific discovery of our era: a cheap, easy way of rewriting genetic code, with nearly limitless promise and peril. Doudna is one of the people who has been involved in developing CRISPR and recognising its potential, and her book co. Great book not recommended for creationists, well maybe the open minded. Author is making a serious effort to speak publicly beyond the scientific community about potential rules and implications, in general she sees plant/animal modifications as obvious (wheat, pork - already fully/exclusively domesticated species), is worried about germline / gene drive changes to. Let us know what’s wrong with this preview of, Published While I appreciated and was fascinated by the science detailed in this book, I was frankly incredulous about Doudna's reaction to the effects CRISPR have wrought in the world because I do not see how anyone could have failed to see them coming. nonetheless, cat is out of bag, so the limits of the technology will ultimately decide where this goes. “The disjunction between scientific consensus and public opinion on the topic of GMOs is disturbing, to say the least.”, “The power to control our species’ genetic future is awesome and terrifying. I found this book equally informative and annoying. a pioneer in the discovery and dissemination of a species altering scientific breakthrough. This is simply amazing research and I am in awe of Doudna. The pace of discovery of new applications of this stunningly powerful tool surpasses any technological change I've followed, including the exponential explosion of digital technology. Prime members enjoy Free Two-Day Shipping, Free Same-Day or One-Day Delivery to select areas, Prime Video, Prime Music, Prime Reading, and more. Doudna does mention the work of others, but it's clear she considers it her discovery. A must for any person interested in genetics and it’s impacts on society. If you haven’t heard of CRISPR before, chances are you’ll be hearing of it again pretty soon. DR. SAMUEL H. STERNBERG is a protein-RNA biochemist and author of numerous high-profile scientific publications on CRISPR technology. The biology of CRISPR/CAS in book are well done, but the ethics of its use less so -both in terms of clarity and thoughtfulness (not surprising given authors' background), but also some very wishful thinking (including little consideration of the inevitability of the race to the bottom (due market forces and large differences in regulation among countries). The pace of discovery of new applications of this stunningly powerful tool surpasses any technological change I've followed, including the exponential explosion of di. I couldn't help but thinking the whole time I spent reading it that it seemed an awful lot like reading "The Double Helix" by James Watson, who only gave passing mention to the contributions of Rosalind Franklin - whose work without which he and Crick would not have "discovered" that DNA is in a double helix form. Please try again. It would give you a great overview of genes & genetics. The scientific explanations are concise and distill what I'm sure are really complex processes into something digestible - and does a much better job of this than Siddhartha Mukherjee's book, in my opinion. Jennifer Doudna, the world-famous scientist behind CRISPR, ‘one of the most monumental discoveries in biology’ (New York Times), explains its discovery, describes its power to reshape the future of all life and warns of its use. The first half of the book explains the basics of DNA, the central dogma, the massive, ancient (and still ongoing) virus-bacteria molecular warfare, the historical context of gene editing research, and finally how CRISPR was discovered and why it is such a big deal. The subject matter is interesting, but I felt that the interesting details of the science were often absent- sections would say "an experiment found that" without any details of how the experiment was designed, or why it had been designed a certain way. See all 6 questions about A Crack in Creation…, 48 Horror Recommendations to Suit Your Reading Mood. It was through her research on viruses that she accidentally found herself in this entirely different scientific arena. Best book in CRISPR . Your recently viewed items and featured recommendations, Select the department you want to search in. Something we hope you'll especially enjoy: FBA products qualify for FREE Shipping. Her obliviousness (honestly, I don't know what else to call it) lends credence to the idea that scientists are disconnected. It’s an amazing tool which could completely revolutionise gene editing, allowing very precise changes to be made with very little unintended impact. A Crack in Creation: Gene Editing and the Unthinkable Power to Control Evolution. To calculate the overall star rating and percentage breakdown by star, we don’t use a simple average. CRISPR provides flawed humanity with the power to create new crops with unquestionably positive impacts on health and environment, to eliminate some genetically based diseases and conditions (sickle cell, some forms of muscular dystrophy), and, much more ambiguously, to breed miniature pig pets and maybe unicorns. Last time a book gave me this feeling of awe and amazement was reading Stephen Hawkin's "Brief history of time" 20 years ago. Is it recommended to read this book ahead of Siddharta Mukherjee's 'The Gene'? A Crack in Creation: Gene Editing and the Unthinkable Power to Control Evolution - Kindle edition by Doudna, Jennifer A., Sternberg, Samuel H.. Download it once and read it on your Kindle device, PC, phones or tablets. The cheapest, simplest, most effective way of manipulating DNA ever known, CRISPR may well give us the cure to HIV, genetic diseases, and some cancers, and will help address the world’s hunger crisis. Sold by Inspire CMC Inc. and ships from Amazon Fulfillment. This book a great, mostly understandable primer on the development and technologies used. It’s starting to be used in clinical trials to edit the genes of human embryos, and it’s already being used in countless research projects. While I appreciated her attempting to discuss. My experience of this book comes in 3 parts. 1-Click ordering is not available for this item. (246pp. In order to navigate out of this carousel, please use your heading shortcut key to navigate to the next or previous heading. Very similar to Watson's "The Double Helix", this book is a part story of discovery and part a textbook, in this case on the topic of CRISPR, from a scientist deeply and technically involved in the technology. Before you start Complete A Crack in Creation: Gene Editing and the Unthinkable Power to Control Evolution PDF EPUB by Jennifer A. Doudna Download, you can read below technical ebook details: If you are still wondering how to get free PDF EPUB of book A Crack in Creation: Gene Editing and the Unthinkable Power to Control Evolution by Jennifer A. Doudna. " A Crack in Creation chronicles the origin and potential application of CRISPR, the powerful new gene-editing technique that established Doudna as a household name in scientific circles. It is really, really good. From studying how bacteria fight off viral infections to development of the Life (not personal but humanity) changing technologies of CRISPR/Cas9. Deciding how to handle it may be the biggest challenge we have ever faced.”, Los Angeles Times Book Prize Nominee for Science & Technology (2017), Goodreads Choice Award Nominee for Science & Technology (2017). The two books are not really related. While I appreciated and was fascinated by the science detailed in this book, I was frankly incredulous about Doudna's reaction to the effects CRISPR have wrought in the world because I do not see how anyone could have failed to see them coming. A great explanation of CRISPR Cas9 that recounts the research that uncovered it and makes a case for determining how we will responsibly control and wield this powerful tool in future gene editing. These items are shipped from and sold by different sellers. Both books seem to talk about genetics, and I'm not sure if this book would make any reference to the other. Reads like a thriller and the discovery of Crispr - Cas 9 has the potential for tremendous public good as long as it does not fall into the wrong hands. Definitely would recommend it to all of my friends, even people who don't study anything related to it, because Dr. Doudna does an amazing job at explaining all the necessary concepts very shortly and easily, so that anybody can understand even if they don't have a scientific background. With CRISPR, she shows, we have effectively taken control of evolution. No Kindle device required. It would give you a great overview of genes & genetics. Jennifer Doudna didnt set out with the intent to create something so world changing when she became a biochemist. Have you ever studied viruses or plasmids and been amazed at how a virus knows how to cut into a gene sequence and take over a cell and eventually tons of cells inside an entire organisms? The Title and the Conclusions Don't Match. Damit man weiß, was auf die Menschheit zukommt - der Missbrauch der Methode findet schon statt, für Geld findet immer irgend ein Wissenschaftler. Refresh and try again. text + endmatter), ISBN 9780544716940, Dewey 576.5072, Library-of-Congress QH440, If you haven’t heard of CRISPR before, chances are you’ll be hearing of it again pretty soon. The two books are not really related. "[A Crack in Creation] opens with the stark observation that the revolution in gene editing launched by CRISPR 'offers both the greatest promise and, arguably, the greatest peril for the future of humanity.' The technology of gene editing is going to have some serious ramifications in perhaps the near future. Click on below buttons to start Download A Crack in Creation: Gene Editing and the Unthinkable Power to Control Evolution by Jennifer A. Doudna PDF EPUB without registration. 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